Albinism is characterized by white skin due to a defect in the enzyme arginase (1) tyrosinase (2), which leads to a block in the pathway needed to synthesize adrenaline (3) / melanin (4). Animals with this condition have a(n) increased (5) / decreased (6) risk of skin cancer. The genetic disease phenylketonuria is caused by a defect in the enzyme tyrosine (7) / phenylalanine (8) hydroxylase, which leads to mental deficiencies caused by a decrease (9) / increase (10) of phenylalanine derivatives that are toxic metabolites.
Choose the best underline word or phrase that correctly completes the sentence and record the numbers.