I am a University Distinguished Professor in the Department of Chemistry & Biochemistry at the University of Arizona in Tucson. My research focus for the past 30 years has been on regulatory mechanisms governing signal transduction in eukaryotic cells. For much of this time, my lab investigated steroid hormone signaling in human disease models, primarily cancer (leukemia and prostate cancer) and asthma. More recently, my research group has been studying metabolic regulation of blood meal metabolism and eggshell development in Aedes mosquitoes, which transmit the dengue and Zika viruses. I have taught a variety of undergraduate, graduate, and medical school biochemistry courses over the past 30-plus years. I currently teach undergraduate biochemistry using both a hybrid class model for in-person courses and a fully online format.
I received my BS and MS degrees in cell biology from San Diego State University and earned a PhD in biochemistry with Norman Arnheim at Stony Brook University, New York. I was a Jane Coffin Childs Fellow and Leukemia & Lymphoma Society Scholar in the Department of Biochemistry and Biophysics at the University of California, San Francisco, with Keith R. Yamamoto before becoming a faculty member at the University of Arizona in 1987.
I have authored four textbooks, including Biochemistry (1e) published in July 2017 and the 2nd Edition of Biochemistry (2e) in July 2021. Two other textbooks are Applied Molecular Genetics (1999) and Biochemistry: A Short Course (1997).