Professor Miesfeld at the University of Arizona
This Online Biochemistry Course is based on Miesfeld’s Biochemistry (3rd Edition)
Cells run unfavorable (endergonic) reactions by coupling them to favorable (exergonic) reactions that share a common intermediate, with ATP hydrolysis as the main energy source. This video covers how the energy charge of the cell sets the balance between catabolic and anabolic pathways.
Key concepts covered: coupled reactions, shared intermediates, additive ΔG, Le Chatelier’s principle, ATP hydrolysis, phosphoanhydride bonds, phosphoryl transfer, energy charge (ATP/ADP/AMP), catabolic vs. anabolic regulation.
Everyday BioChem 