Professor Miesfeld at the University of Arizona
This Online Biochemistry Course is based on Miesfeld’s Biochemistry (3rd Edition)
Energy balance holds when the calories you eat match the calories you burn. This video covers how leptin, insulin, ghrelin, PYY, and GLP-1 signal to neurons in the hypothalamus to control appetite and metabolism, and how this connects to obesity, type 2 diabetes, and GLP-1 drugs such as semaglutide.
Key concepts covered: energy balance, thrifty gene hypothesis, leptin and adipose signaling, POMC and NPY/AGRP neurons, anorexigenic vs. orexigenic pathways, insulin, ghrelin, PYY3-36, GLP-1 receptor and semaglutide, obesity and type 2 diabetes.
Everyday BioChem 